ZOLOFT 50MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Sertraline Hydrochloride 50mg

MANUFACTURER: Pfizer Pakistan Ltd

QUANTITY:

Pack of 30 tablets

INDICATION

Zoloft 50mg Tab is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder with or without agoraphobia, post-traumatic stress disorder (PTSD), social anxiety disorder, premenstrual dysphoric disorder (PMDD), and as the most prescribed SSRI for depression in both adults and children aged 6 years and older for OCD.

MECHANISM OF ACTION

Sertraline selectively inhibits the neuronal reuptake of serotonin by blocking the serotonin transporter (SERT) with high potency and selectivity, increasing serotonin availability in the synaptic cleft. It has minimal affinity for dopamine, norepinephrine, muscarinic, histaminergic, or adrenergic receptors, resulting in a clean tolerability profile with fewer anticholinergic and cardiovascular side effects than older antidepressants. Sertraline undergoes extensive first-pass metabolism to its active N-desmethyl metabolite, which contributes minimally to its overall pharmacological effect.

DOSAGE AND ADMINISTRATION

•      Depression: 50mg once daily in the morning or evening; may increase to 100 to 200mg per day at intervals of at least 1 week

•      OCD: 50mg once daily; usual effective dose 50 to 200mg/day

•      Panic disorder and PTSD: start 25mg once daily for the first week, then increase to 50mg

•      Always follow the dosage and titration schedule prescribed by your psychiatrist; may take 4 to 8 weeks for full effect

SIDE EFFECTS

Common:

•      Nausea and diarrhoea (most common, usually transient)

•      Headache and dizziness

•      Insomnia or somnolence

•      Dry mouth and sweating

Less common:

•      Sexual dysfunction: reduced libido, delayed orgasm, erectile dysfunction

•      Weight changes with prolonged use

•      Hyponatremia, particularly in elderly patients

•      Serotonin syndrome when combined with other serotonergic drugs (rare)

NOT RECOMMENDED IN

•      Concurrent use with MAO inhibitors (14-day washout required)

•      Concurrent use with pimozide (QT prolongation risk)

•      Known hypersensitivity to sertraline

•      Children under 6 years of age

DRUG INTERACTIONS

MAO inhibitors are contraindicated; 14-day washout in both directions. Pimozide is absolutely contraindicated due to QT prolongation risk. Sertraline is a moderate CYP2D6 inhibitor and may increase levels of tricyclics, antipsychotics, and some beta-blockers. Anticoagulant effect of warfarin may be enhanced; monitor INR. NSAIDs and aspirin increase bleeding risk due to platelet serotonin depletion.

STORAGE INSTRUCTIONS

Store below 25°C in a dry place away from direct sunlight and moisture. Keep in original blister packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Zoloft 50mg Tab 30S online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Zoloft 50mg tab price in pakistan and learn about Zoloft 50mg tab uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Zoloft 50mg tab uses, pricing, and order placement.