TERLIP 1MG INJECTION ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Terlipressin Acetate 1mg

MANUFACTURER: Getz Pharma (Pvt) Ltd

QUANTITY:

Single vial for injection

INDICATION

Terlip 1mg Inj is a synthetic vasopressin analogue indicated for the treatment of bleeding esophageal varices in patients with portal hypertension due to liver cirrhosis. It is also used in hepatorenal syndrome to improve renal perfusion and in septic shock refractory to norepinephrine.

MECHANISM OF ACTION

Terlipressin is a prodrug that is enzymatically converted to lysine-vasopressin in body tissues. Lysine-vasopressin acts on vasopressin V1 receptors on vascular smooth muscle, causing splanchnic and systemic vasoconstriction. In variceal bleeding, this reduces portal venous blood flow and portal pressure, controlling hemorrhage from esophageal varices. In hepatorenal syndrome, it reverses splanchnic vasodilation, improving effective arterial blood volume and renal perfusion. Its longer half-life than vasopressin allows intermittent bolus dosing rather than continuous infusion.

DOSAGE AND ADMINISTRATION

•      Variceal bleeding: 1 to 2mg by slow intravenous injection every 4 to 6 hours until hemostasis, for up to 72 hours

•      Hepatorenal syndrome: 0.5 to 1mg every 4 to 6 hours, titrated to response

•      Administered by slow intravenous injection by trained healthcare professionals only

•      Always prescribed and monitored by a specialist; not for self-administration

SIDE EFFECTS

Common:

•      Abdominal cramps and diarrhoea

•      Hypertension

•      Pallor and sweating

•      Headache

Less common:

•      Cardiac arrhythmias and bradycardia

•      Peripheral and mesenteric ischemia

•      Respiratory failure (monitor oxygen saturation continuously)

•      Hyponatremia with prolonged use

NOT RECOMMENDED IN

•      Known hypersensitivity to Terlipressin or vasopressin analogues

•      Pregnancy (causes uterine contractions and fetal harm)

•      Septic shock with severe hypoxia

•      Severe cardiovascular disease including unstable angina or recent myocardial infarction

DRUG INTERACTIONS

Terlipressin combined with beta-blockers and digoxin increases the risk of cardiac arrhythmias; monitor ECG during co-administration. NSAIDs may reduce the renal benefit in hepatorenal syndrome. Concurrent vasopressors require careful hemodynamic monitoring to avoid excessive hypertension. Albumin infusion is routinely co-administered with Terlipressin in hepatorenal syndrome to improve efficacy.

STORAGE INSTRUCTIONS

Store between 2°C and 8°C (refrigerate). Protect from light and heat. Do not freeze. Keep out of reach of children.

WHERE TO BUY

You can buy Terlip 1mg Inj online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Terlip 1mg Inj price in pakistan and learn about Terlip 1mg Inj uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Terlip 1mg Inj uses, pricing, and order placement.