TERLAX 2MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Tizanidine Hydrochloride 2mg

MANUFACTURER: Barretts Hodgson Pakistan (Pvt) Ltd

QUANTITY:

Pack of 10 tablets

INDICATION

Terlax 2mg Tab is a centrally acting alpha-2 adrenergic agonist used as a muscle relaxant for the management of spasticity associated with neurological conditions including multiple sclerosis, spinal cord injury, and stroke. It is also used for acute muscle spasm and painful musculoskeletal conditions.

MECHANISM OF ACTION

Tizanidine acts as a selective agonist at alpha-2 adrenergic receptors in the spinal cord and brainstem, enhancing presynaptic inhibition of motor neurons. By increasing inhibitory neurotransmission, it reduces the release of excitatory amino acids (glutamate and aspartate) from spinal interneurons, decreasing polysynaptic reflex activity and lowering skeletal muscle tone. This central mechanism reduces spasticity without the peripheral neuromuscular blockade of agents like baclofen, and with less sedation than diazepam at equivalent antispastic doses.

DOSAGE AND ADMINISTRATION

•      Initial dose: 2mg once daily at night to minimize daytime sedation

•      Increase by 2mg every 3 to 4 days based on response and tolerability

•      Usual effective dose: 6 to 12mg per day in 3 divided doses; maximum 36mg per day

•      Always follow the dose titration schedule prescribed by your neurologist; never stop abruptly

SIDE EFFECTS

Common:

•      Somnolence and sedation (most common)

•      Dizziness and dry mouth

•      Hypotension (low blood pressure)

•      Fatigue and weakness

Less common:

•      Elevated liver enzymes and hepatotoxicity (monitor LFTs in first 6 months of therapy)

•      Hallucinations and confusion

•      Bradycardia

•      Rebound hypertension and tachycardia on abrupt discontinuation

NOT RECOMMENDED IN

•      Severe hepatic impairment (hepatotoxicity risk; monitor LFTs carefully)

•      Concurrent use with fluvoxamine or ciprofloxacin (potent CYP1A2 inhibitors; markedly increase tizanidine exposure)

•      Concurrent use with other antihypertensives or alpha-2 agonists (additive hypotension)

•      Known hypersensitivity to tizanidine

DRUG INTERACTIONS

CYP1A2 inhibitors, particularly fluvoxamine and ciprofloxacin, dramatically increase tizanidine plasma levels, leading to severe hypotension, bradycardia, and sedation; these combinations are contraindicated. Oral contraceptives containing estrogen reduce CYP1A2 activity and increase tizanidine levels by approximately 50%; reduce tizanidine dose accordingly. CNS depressants including alcohol, benzodiazepines, and opioids add to sedation. Antihypertensives produce additive hypotensive effects.

STORAGE INSTRUCTIONS

Store below 25°C in a dry place away from direct sunlight and moisture. Keep in original blister packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Terlax 2mg Tab 10S online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Terlax 2mg tab price in pakistan and learn about Terlax 2mg tab uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Terlax 2mg tab uses, pricing, and order placement.