SILORAP 8MG CAPSULE ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Silodosin 8mg

MANUFACTURER: Getz Pharma (Pvt) Ltd

QUANTITY:

Pack of 20 capsules

INDICATION

Silorap 8mg Caps is the standard full dose of silodosin indicated for the symptomatic treatment of benign prostatic hyperplasia (BPH) in adult men with normal or mildly reduced renal function. It provides more complete alpha-1A receptor blockade in the prostate, improving urinary flow rate and reducing BPH symptoms.

MECHANISM OF ACTION

At 8mg, silodosin achieves higher receptor occupancy at prostate alpha-1A receptors, producing maximal smooth muscle relaxation in the prostate and bladder outlet. This improves peak urinary flow rate (Qmax) and reduces the International Prostate Symptom Score (IPSS) more effectively than the 4mg dose. The selectivity for prostatic alpha-1A receptors over vascular alpha-1B receptors remains high at this dose, minimizing postural hypotension while delivering full therapeutic benefit.

DOSAGE AND ADMINISTRATION

•      Adults with normal renal function: 8mg once daily with a meal

•      Do not use in patients with severe renal impairment (CrCl below 30 ml/min)

•      Take consistently with food at the same time each day

•      Always follow the dosage prescribed by your urologist

SIDE EFFECTS

Common:

•      Retrograde ejaculation (occurs in approximately 20 to 28% of patients at 8mg)

•      Dizziness and orthostatic hypotension

•      Nasal congestion

•      Diarrhoea

Less common:

•      Intraoperative floppy iris syndrome (IFIS) during cataract surgery

•      Syncope in susceptible patients

•      Headache

•      Elevated liver transaminases (rare)

NOT RECOMMENDED IN

•      Severe renal impairment (CrCl below 30 ml/min)

•      Severe hepatic impairment

•      Strong CYP3A4 inhibitors

•      Not indicated in women or children

DRUG INTERACTIONS

Same as 4mg dose but with higher baseline exposure. Strong CYP3A4 inhibitors markedly increase silodosin levels; contraindicated. PDE5 inhibitors add to blood pressure reduction. P-glycoprotein inhibitors increase exposure. Antihypertensives may produce additive hypotension.

STORAGE INSTRUCTIONS

Store below 25°C in a dry place away from direct sunlight and moisture. Keep in original packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Silorap 8mg caps 20S online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Silorap 8mg caps price in pakistan and learn about Silorap 8mg capsules uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Silorap 8mg capsules uses, pricing, and order placement.