Rovista Ez 5+10mg Tablets Online At Best Price In Pakistan

Generic: Rosuvastatin 5mg + Ezetimibe 10mg

Manufacturer: Getz Pharma

Quantity:

10 Tablets per pack

INDICATION

Rovista EZ 5mg+10mg Tab is a dual-action cholesterol-lowering combination therapy indicated for the management of primary hypercholesterolemia and mixed dyslipidemia in adults where single-agent therapy proves insufficient. Combining a statin with a cholesterol absorption inhibitor, it provides a more comprehensive reduction in LDL cholesterol than either drug alone. It is used to lower total cholesterol, LDL cholesterol, and triglycerides while raising HDL cholesterol, thereby significantly reducing the risk of cardiovascular disease, heart attacks, and stroke.

MECHANISM OF ACTION

Rovista EZ combines two complementary mechanisms. Rosuvastatin, a statin, inhibits the HMG-CoA reductase enzyme in the liver, reducing the liver's internal cholesterol production. As a result, the liver draws more LDL cholesterol from the bloodstream to compensate, effectively lowering circulating LDL levels. Ezetimibe works in the small intestine, blocking a specific protein called NPC1L1 that is responsible for absorbing dietary and biliary cholesterol from food. By inhibiting this absorption, less cholesterol enters the bloodstream. Together, both drugs attack cholesterol from two fronts, delivering a significantly greater reduction in lipid levels.

DOSAGE AND ADMINISTRATION

•      One tablet once daily, taken orally with or without food.

•      Dosage adjustments should only be made by a physician based on lipid response.

•      Continue alongside a physician-recommended low-cholesterol diet and exercise plan.

SIDE EFFECTS

•      Common: Headache, myalgia, nausea, abdominal pain, diarrhea.

•      Less common: Elevated liver enzymes, muscle weakness, fatigue, and blood sugar elevation (rare).

NOT RECOMMENDED IN

Rovista EZ 5mg+10mg Tab is contraindicated in patients with active liver disease, unexplained persistent elevation of liver enzymes, or known hypersensitivity to rosuvastatin or ezetimibe. It is not recommended during pregnancy or breastfeeding. Patients with severe renal impairment or unexplained muscle disorders should not use this medication without specialist evaluation. Excessive alcohol consumption should be avoided during therapy as it increases the risk of liver-related adverse effects.

DRUG INTERACTIONS

Rosuvastatin in this combination may interact with cyclosporine, gemfibrozil, niacin, antiretroviral drugs, and antacids, altering its plasma levels or increasing the risk of myopathy. Ezetimibe may be affected by bile acid sequestrants, which reduce its absorption; a minimum four hour gap is advised. Warfarin interaction has been reported; INR should be monitored in patients on anticoagulant therapy. Co-administration with fibrates increases the overall myopathy risk. Patients must share their complete medication list with their physician before starting this combination.

STORAGE INSTRUCTIONS

Store in a cool, dry place at room temperature below 30°C. Protect from light and moisture. Keep in original packaging. Store out of reach of children. Do not use after the expiry date on the carton.

WHERE TO BUY

Dawa Healthcare Pharmacy offers a seamless way to buy Rovista EZ 5mg+10mg Tab online in Pakistan, giving patients easy access to this important dual-action cholesterol therapy. For those looking up the Rovista EZ 5mg+10mg tablets price in Pakistan, our platform provides consistently reliable and transparent pricing. Order Rovista EZ 5mg+10mg Tab online today and enjoy same-day delivery within Karachi for orders placed before the daily cut-off, with courier-based delivery services reaching patients in all cities across Pakistan. Our knowledgeable team is available on WhatsApp, and our branches are conveniently distributed throughout Karachi.