PRESTIA 40MG INJECTION ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Methylprednisolone Sodium Succinate 40mg

MANUFACTURER: Horizon Pharmaceuticals (Pvt) Ltd

QUANTITY:

Single vial for injection

INDICATION

Prestia 40mg Inj is a corticosteroid indicated for the treatment of moderate inflammatory, allergic, and immunological conditions requiring parenteral corticosteroid therapy. It is used in acute allergic reactions, asthma exacerbations, inflammatory joint conditions, dermatological conditions, and situations where oral corticosteroid therapy is not feasible.

MECHANISM OF ACTION

Methylprednisolone is a synthetic glucocorticoid that binds to intracellular glucocorticoid receptors and modulates the transcription of anti-inflammatory genes. It inhibits the synthesis of pro-inflammatory cytokines including IL-1, IL-6, and TNF-alpha, reduces vascular permeability, suppresses leukocyte migration to sites of inflammation, and stabilizes cell membranes. The sodium succinate ester is water-soluble, allowing rapid intravenous or intramuscular administration. The 40mg dose provides effective anti-inflammatory activity suitable for moderate inflammatory conditions and serves as the standard dose for many acute indications in outpatient and emergency settings.

DOSAGE AND ADMINISTRATION

•      Adults: 40mg by intramuscular or intravenous injection; frequency and duration determined by condition

•      Acute allergic reactions and asthma: 40 to 80mg IV or IM as a single or repeat dose

•      Inflammatory joint conditions: 40mg by intra-articular or soft tissue injection as directed

•      Always administered by a trained healthcare professional; dosage adjusted by the prescribing physician based on clinical response

SIDE EFFECTS

Common:

•      Elevated blood glucose, particularly in diabetic patients

•      Fluid retention and mild oedema

•      Elevated blood pressure

•      Flushing and mild mood changes

Less common:

•      Adrenal suppression with repeated or prolonged use

•      Increased susceptibility to infections

•      Peptic ulceration, particularly with concurrent NSAID use

•      Injection site reactions with intramuscular administration

NOT RECOMMENDED IN

•      Systemic fungal infections

•      Known hypersensitivity to methylprednisolone or any excipient

•      Live vaccines should not be administered concurrently with systemic corticosteroid therapy

•      Use with caution in patients with diabetes, hypertension, active infections, or peptic ulcer disease

DRUG INTERACTIONS

NSAIDs combined with methylprednisolone significantly increase the risk of gastrointestinal ulceration and bleeding; avoid concurrent use where possible. CYP3A4 inhibitors such as ketoconazole, clarithromycin, and ritonavir increase methylprednisolone plasma levels, enhancing both therapeutic and adverse effects. CYP3A4 inducers including rifampicin, carbamazepine, and phenytoin reduce methylprednisolone efficacy. Antidiabetic drug doses may need adjustment as corticosteroids raise blood glucose levels.

STORAGE INSTRUCTIONS

Store unconstituted vials below 25°C away from direct light. Use reconstituted solution immediately or within the stability period stated on the label. Keep out of reach of children.

WHERE TO BUY

You can buy Prestia 40mg Inj IM/IV online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Prestia 40mg Inj IM/IV price in pakistan and learn about Prestia 40mg Inj IM/IV uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Prestia 40mg Inj IM/IV uses, pricing, and order placement.