OPT-D 1 LAC IU CAPSULE ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Cholecalciferol (Vitamin D3) 100,000 IU (1 Lac IU)

MANUFACTURER: Pharm Evo (Pvt) Ltd

QUANTITY:

Pack of 2 capsules

INDICATION

Opt-D 1 Lac IU Cap is a high-dose vitamin D3 supplement indicated for the treatment of vitamin D deficiency and insufficiency, osteomalacia, rickets, and secondary hyperparathyroidism due to vitamin D deficiency. It is prescribed as a loading dose regimen to rapidly correct established vitamin D deficiency.

MECHANISM OF ACTION

Cholecalciferol is the natural form of vitamin D3 synthesized in the skin under ultraviolet B light exposure. Following oral ingestion, it is hydroxylated in the liver to 25-hydroxyvitamin D (calcidiol) and then in the kidney to the biologically active form, 1,25-dihydroxyvitamin D (calcitriol). Calcitriol acts on vitamin D receptors in the intestinal mucosa to enhance calcium and phosphorus absorption, promotes calcium mobilization from bone, and reduces renal calcium excretion, collectively maintaining calcium homeostasis, supporting bone mineralization, and modulating immune function.

DOSAGE AND ADMINISTRATION

•      Loading dose regimen: 1 capsule (100,000 IU) weekly or fortnightly as prescribed

•      Duration and frequency determined by baseline serum 25-OH vitamin D levels

•      Swallow whole with water; may be taken with or without food

•      Always follow the prescribed dosing schedule; do not self-administer high doses without monitoring

SIDE EFFECTS

Common:

•      Generally, well tolerated at prescribed therapeutic doses

•      Mild nausea or stomach discomfort

•      Headache

•      Constipation

Less common:

•      Hypercalcemia with excessive or prolonged high-dose use: thirst, frequent urination, weakness, confusion

•      Kidney stones with prolonged hypercalcemia

•      Hypercalciuria

•      Raised serum calcium leading to cardiovascular effects at toxic doses

NOT RECOMMENDED IN

•      Hypercalcemia or hypercalciuria

•      Known hypersensitivity to cholecalciferol

•      Severe renal impairment or nephrolithiasis

•      Do not take alongside other vitamin D supplements without monitoring serum levels

DRUG INTERACTIONS

Thiazide diuretics combined with high-dose vitamin D increase the risk of hypercalcemia; monitor serum calcium. Orlistat, cholestyramine, and mineral oil reduce fat-soluble vitamin D absorption; take separately. Antiepileptics including phenytoin, carbamazepine, and phenobarbitone increase vitamin D catabolism, requiring higher supplementation doses. Vitamin D toxicity risk increases with concurrent use of other vitamin D preparations.

STORAGE INSTRUCTIONS

Store below 25°C in a dry place away from direct sunlight. Keep in original packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Opt-D 1lac IU Cap 2S online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Opt-D 1lac IU Cap 2S price in Pakistan and learn about Opt-D 1lac IU capsule uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Opt-D 1lac IU capsule uses, pricing, and order placement.