NEPAFEN 0.1% 5ML DROP ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Nepafenac 0.1%

MANUFACTURER: Shaigan Pharmaceuticals

QUANTITY

5ml eye drops

INDICATION

Nepafen 0.1% Drops are a non-steroidal anti-inflammatory ophthalmic suspension indicated for the treatment of pain and inflammation associated with cataract surgery. Nepafenac is also indicated for the reduction in the risk of postoperative macular edema following cataract surgery in diabetic patients. It is used starting 1 day before surgery, continued on the day of surgery, and for 2 weeks postoperatively.

MECHANISM OF ACTION

Nepafenac is a prodrug that penetrates the cornea rapidly due to its uncharged structure. Once inside the eye, it is converted by intraocular tissue hydrolases to its active metabolite amfenac, a potent inhibitor of cyclooxygenase-1 and cyclooxygenase-2. By blocking prostaglandin synthesis at the site of ocular inflammation, amfenac reduces pain, swelling, and the risk of cystoid macular edema. The prodrug design allows faster corneal penetration and higher intraocular drug concentrations compared to conventional ophthalmic NSAIDs.

DOSAGE AND ADMINISTRATION

·        Instill 1 drop in the affected eye(s) 3 times daily, beginning 1 day before cataract surgery

·        Continue on the day of surgery and for 2 weeks after surgery

·        Shake the bottle well before each use as the formulation is a suspension

·        Do not wear contact lenses during treatment

·        Space at least 5 minutes between this and other eye drop preparations

·        Begin treatment within the prescribed timeframe relative to surgery for optimal benefit

SIDE EFFECTS

Common:

·        Mild stinging and burning upon instillation

·        Eye redness and irritation

·        Blurred vision immediately after application

·        Sticky sensation in the eye

Less common:

·        Corneal epithelial defects and delayed wound healing

·        Corneal thinning or perforation, particularly with prolonged use or in predisposed patients

·        Allergic reactions including eyelid edema and pruritus

·        Increased intraocular pressure (rare)

NOT RECOMMENDED IN

Known hypersensitivity to nepafenac or any NSAID

Patients with a history of complicated or prolonged corneal healing

Active corneal epithelial defect

Use beyond the recommended 14-day postoperative period without ophthalmologist approval

DRUG INTERACTIONS

Concurrent use with topical corticosteroids may increase the risk of corneal adverse events. Topical NSAIDs may slow corneal wound healing. There is a potential additive bleeding risk with systemic anticoagulants, though ocular absorption is limited. Avoid concurrent use with other ophthalmic NSAIDs.

STORAGE INSTRUCTIONS

Store at room temperature between 2 to 25 degrees Celsius. Do not freeze. Shake well before use. Discard 4 weeks after first opening. Keep the bottle tightly closed. Keep out of reach of children.

WHERE TO BUY

Dawa Healthcare Pharmacy at dawahealthcare.biz carries Nepafen 0.1% 5ml Drops for post-cataract surgery care. Find the Nepafen 0.1% 5ml Drop price in Pakistan and learn about Nepafen 0.1% 5ml Drop uses for surgical eye inflammation, pain management, and macular edema prevention on our product page. Dawa Healthcare branches across Karachi stock surgical ophthalmic products under pharmacist supervision. Same-day delivery covers all Karachi areas, and nationwide courier service delivers across Pakistan. WhatsApp ordering at each branch connects you with a pharmacist for dosing and timing guidance.