Linjardy 5/10mg Tablets Online At Best Price In Pakistan

GENERIC: Linagliptin 5mg + Empagliflozin 10mg

MANUFACTURER: CCL Pharmaceuticals (Pvt.) Ltd.

QUANTITY

14 Tablets

INDICATION

Linjardy 5/10mg is a fixed-dose combination tablet indicated for the management of type 2 diabetes mellitus in adults. It combines two complementary mechanisms to provide better glycemic control than either agent alone. Linagliptin improves insulin secretion in a glucose-dependent manner while empagliflozin reduces blood glucose through increased urinary glucose excretion. This combination is particularly beneficial for patients who require dual antidiabetic therapy to achieve target HbA1c levels.

MECHANISM OF ACTION

Linagliptin inhibits dipeptidyl peptidase-4 (DPP-4), an enzyme responsible for the degradation of incretin hormones GLP-1 and GIP. By increasing active incretin levels, it enhances glucose-dependent insulin secretion and reduces glucagon release. Empagliflozin works as a sodium-glucose co-transporter-2 (SGLT2) inhibitor, blocking renal glucose reabsorption in the proximal tubule and promoting urinary glucose excretion. Together, these two mechanisms deliver complementary glycemic benefits.

DOSAGE AND ADMINISTRATION

•      Recommended dose: One tablet (5mg/10mg) once daily in the morning.

•      Take with or without food.

•      Not recommended in patients with eGFR below 45 mL/min/1.73m².

•      Dose should be individualized based on renal function and patient tolerability.

•      Consult a physician before initiating therapy in elderly patients.

SIDE EFFECTS

•      Urinary tract infections

•      Genital mycotic infections

•      Nasopharyngitis

•      Increased urination

•      Hypoglycemia (especially when combined with insulin or sulfonylureas)

NOT RECOMMENDED IN

Linjardy 5/10mg is contraindicated in patients with type 1 diabetes mellitus, severe renal impairment (eGFR <45), or diabetic ketoacidosis. It should not be used in patients with a history of recurrent urinary tract or genital infections. Caution is needed in elderly patients or those prone to hypotension. Not recommended during pregnancy or breastfeeding. Patients undergoing major surgical procedures should temporarily discontinue use as advised by their physician.

DRUG INTERACTIONS

The combination of linagliptin and empagliflozin may interact with diuretics, increasing the risk of dehydration and hypotension, particularly in elderly patients. Co-administration with insulin or insulin secretagogues such as sulfonylureas may increase hypoglycemia risk; dose reduction of the latter may be needed.

STORAGE INSTRUCTIONS

Store at room temperature below 30°C. Keep away from moisture, heat, and direct sunlight. Store in original blister packaging. Keep out of reach of children.

WHERE TO BUY

Linjardy 5/10mg Tab is available online through Dawa Healthcare Pharmacy, offering genuine diabetic medicines at competitive prices. Customers searching for Linjardy 5/10mg tablets price in Pakistan can find up-to-date pricing along with easy and secure ordering options on the platform. Ordering online is simple and convenient, with reliable nationwide delivery services and same-day delivery available in Karachi. Dawa Healthcare Pharmacy is a trusted source for prescription medicines and diabetes management products, ensuring quality, authenticity, and proper handling.