
KESTINE 5MG/5ML SYRUP 60ML
KESTINE 5MG/5ML SYRUP 60ML ONLINE AT BEST PRICE IN PAKISTAN
GENERIC: Ebastine 5mg/5ml (Antihistamine Syrup)
MANUFACTURER: Highnoon Pharma
QUANTITY
60 ml syrup
INDICATION
Kestine 5mg/5ml Syrup is a second-generation non-sedating antihistamine indicated for the symptomatic relief of allergic rhinitis (both seasonal and perennial), allergic conjunctivitis, and chronic idiopathic urticaria in adults and children.
MECHANISM OF ACTION
Ebastine is a selective peripheral H1 histamine receptor antagonist. It is rapidly metabolized to its active metabolite carebastine, which competitively blocks H1 receptors on vascular endothelium, smooth muscle, and sensory nerves. This prevents histamine-mediated vasodilation, increased vascular permeability, itching, and bronchoconstriction. Unlike first-generation antihistamines, ebastine has minimal blood-brain barrier penetration and therefore causes negligible sedation.
DOSAGE AND ADMINISTRATION
● Adults and children above 12 years: 10ml (10mg) once daily
● Children 6 to 12 years: 5ml (5mg) once daily
● Children 2 to 6 years: 2.5ml (2.5mg) once daily or as directed
● May be taken with or without food
● Shake well before use
SIDE EFFECTS
Common:
● Headache
● Dry mouth
● Mild drowsiness in sensitive individuals
Less common:
● QTc prolongation at doses exceeding recommended limits
● Abdominal pain in rare cases
● Allergic reactions in very rare cases
NOT RECOMMENDED IN
● Known hypersensitivity to ebastine or any component
● Severe hepatic impairment
● Concurrent use with potent CYP3A4 inhibitors at elevated doses
DRUG INTERACTIONS
CYP3A4 inhibitors such as ketoconazole and erythromycin increase ebastine plasma levels and QTc prolongation risk at doses above 20mg. Avoid concurrent use with other QTc-prolonging medications. No significant interaction at standard doses.
STORAGE INSTRUCTIONS
Store below 25 degrees Celsius. Protect from light. Shake well before use. Keep out of reach of children.
WHERE TO BUY
Dawa Healthcare Pharmacy at dawahealthcare.biz is where you can buy Kestine 5mg/5ml Syrup 60ML online. The Kestine 5mg/5ml Syrup 60ML uses and the Kestine 5mg/5ml Syrup 60ML price in Pakistan are clearly displayed. Multiple Karachi branches with same-day delivery and nationwide shipping across Pakistan. WhatsApp ordering at each branch. Dawa Healthcare provides genuine allergy medications backed by pharmacist expertise.
Original: $220.40
-65%$220.40
$77.14Product Information
Product Information
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Description
KESTINE 5MG/5ML SYRUP 60ML ONLINE AT BEST PRICE IN PAKISTAN
GENERIC: Ebastine 5mg/5ml (Antihistamine Syrup)
MANUFACTURER: Highnoon Pharma
QUANTITY
60 ml syrup
INDICATION
Kestine 5mg/5ml Syrup is a second-generation non-sedating antihistamine indicated for the symptomatic relief of allergic rhinitis (both seasonal and perennial), allergic conjunctivitis, and chronic idiopathic urticaria in adults and children.
MECHANISM OF ACTION
Ebastine is a selective peripheral H1 histamine receptor antagonist. It is rapidly metabolized to its active metabolite carebastine, which competitively blocks H1 receptors on vascular endothelium, smooth muscle, and sensory nerves. This prevents histamine-mediated vasodilation, increased vascular permeability, itching, and bronchoconstriction. Unlike first-generation antihistamines, ebastine has minimal blood-brain barrier penetration and therefore causes negligible sedation.
DOSAGE AND ADMINISTRATION
● Adults and children above 12 years: 10ml (10mg) once daily
● Children 6 to 12 years: 5ml (5mg) once daily
● Children 2 to 6 years: 2.5ml (2.5mg) once daily or as directed
● May be taken with or without food
● Shake well before use
SIDE EFFECTS
Common:
● Headache
● Dry mouth
● Mild drowsiness in sensitive individuals
Less common:
● QTc prolongation at doses exceeding recommended limits
● Abdominal pain in rare cases
● Allergic reactions in very rare cases
NOT RECOMMENDED IN
● Known hypersensitivity to ebastine or any component
● Severe hepatic impairment
● Concurrent use with potent CYP3A4 inhibitors at elevated doses
DRUG INTERACTIONS
CYP3A4 inhibitors such as ketoconazole and erythromycin increase ebastine plasma levels and QTc prolongation risk at doses above 20mg. Avoid concurrent use with other QTc-prolonging medications. No significant interaction at standard doses.
STORAGE INSTRUCTIONS
Store below 25 degrees Celsius. Protect from light. Shake well before use. Keep out of reach of children.
WHERE TO BUY
Dawa Healthcare Pharmacy at dawahealthcare.biz is where you can buy Kestine 5mg/5ml Syrup 60ML online. The Kestine 5mg/5ml Syrup 60ML uses and the Kestine 5mg/5ml Syrup 60ML price in Pakistan are clearly displayed. Multiple Karachi branches with same-day delivery and nationwide shipping across Pakistan. WhatsApp ordering at each branch. Dawa Healthcare provides genuine allergy medications backed by pharmacist expertise.











