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KESTINE 5MG/5ML SYRUP 60ML

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KESTINE 5MG/5ML SYRUP 60ML

KESTINE 5MG/5ML SYRUP 60ML ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Ebastine 5mg/5ml (Antihistamine Syrup)

MANUFACTURER: Highnoon Pharma

QUANTITY

60 ml syrup

INDICATION

Kestine 5mg/5ml Syrup is a second-generation non-sedating antihistamine indicated for the symptomatic relief of allergic rhinitis (both seasonal and perennial), allergic conjunctivitis, and chronic idiopathic urticaria in adults and children.

MECHANISM OF ACTION

Ebastine is a selective peripheral H1 histamine receptor antagonist. It is rapidly metabolized to its active metabolite carebastine, which competitively blocks H1 receptors on vascular endothelium, smooth muscle, and sensory nerves. This prevents histamine-mediated vasodilation, increased vascular permeability, itching, and bronchoconstriction. Unlike first-generation antihistamines, ebastine has minimal blood-brain barrier penetration and therefore causes negligible sedation.

DOSAGE AND ADMINISTRATION

     Adults and children above 12 years: 10ml (10mg) once daily

     Children 6 to 12 years: 5ml (5mg) once daily

     Children 2 to 6 years: 2.5ml (2.5mg) once daily or as directed

     May be taken with or without food

     Shake well before use

SIDE EFFECTS

Common:

     Headache

     Dry mouth

     Mild drowsiness in sensitive individuals

Less common:

     QTc prolongation at doses exceeding recommended limits

     Abdominal pain in rare cases

     Allergic reactions in very rare cases

NOT RECOMMENDED IN

     Known hypersensitivity to ebastine or any component

     Severe hepatic impairment

     Concurrent use with potent CYP3A4 inhibitors at elevated doses

DRUG INTERACTIONS

CYP3A4 inhibitors such as ketoconazole and erythromycin increase ebastine plasma levels and QTc prolongation risk at doses above 20mg. Avoid concurrent use with other QTc-prolonging medications. No significant interaction at standard doses.

STORAGE INSTRUCTIONS

Store below 25 degrees Celsius. Protect from light. Shake well before use. Keep out of reach of children.

WHERE TO BUY

Dawa Healthcare Pharmacy at dawahealthcare.biz is where you can buy Kestine 5mg/5ml Syrup 60ML online. The Kestine 5mg/5ml Syrup 60ML uses and the Kestine 5mg/5ml Syrup 60ML price in Pakistan are clearly displayed. Multiple Karachi branches with same-day delivery and nationwide shipping across Pakistan. WhatsApp ordering at each branch. Dawa Healthcare provides genuine allergy medications backed by pharmacist expertise.

 

$77.14

Original: $220.40

-65%
KESTINE 5MG/5ML SYRUP 60ML

$220.40

$77.14

Product Information

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Description

KESTINE 5MG/5ML SYRUP 60ML ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Ebastine 5mg/5ml (Antihistamine Syrup)

MANUFACTURER: Highnoon Pharma

QUANTITY

60 ml syrup

INDICATION

Kestine 5mg/5ml Syrup is a second-generation non-sedating antihistamine indicated for the symptomatic relief of allergic rhinitis (both seasonal and perennial), allergic conjunctivitis, and chronic idiopathic urticaria in adults and children.

MECHANISM OF ACTION

Ebastine is a selective peripheral H1 histamine receptor antagonist. It is rapidly metabolized to its active metabolite carebastine, which competitively blocks H1 receptors on vascular endothelium, smooth muscle, and sensory nerves. This prevents histamine-mediated vasodilation, increased vascular permeability, itching, and bronchoconstriction. Unlike first-generation antihistamines, ebastine has minimal blood-brain barrier penetration and therefore causes negligible sedation.

DOSAGE AND ADMINISTRATION

     Adults and children above 12 years: 10ml (10mg) once daily

     Children 6 to 12 years: 5ml (5mg) once daily

     Children 2 to 6 years: 2.5ml (2.5mg) once daily or as directed

     May be taken with or without food

     Shake well before use

SIDE EFFECTS

Common:

     Headache

     Dry mouth

     Mild drowsiness in sensitive individuals

Less common:

     QTc prolongation at doses exceeding recommended limits

     Abdominal pain in rare cases

     Allergic reactions in very rare cases

NOT RECOMMENDED IN

     Known hypersensitivity to ebastine or any component

     Severe hepatic impairment

     Concurrent use with potent CYP3A4 inhibitors at elevated doses

DRUG INTERACTIONS

CYP3A4 inhibitors such as ketoconazole and erythromycin increase ebastine plasma levels and QTc prolongation risk at doses above 20mg. Avoid concurrent use with other QTc-prolonging medications. No significant interaction at standard doses.

STORAGE INSTRUCTIONS

Store below 25 degrees Celsius. Protect from light. Shake well before use. Keep out of reach of children.

WHERE TO BUY

Dawa Healthcare Pharmacy at dawahealthcare.biz is where you can buy Kestine 5mg/5ml Syrup 60ML online. The Kestine 5mg/5ml Syrup 60ML uses and the Kestine 5mg/5ml Syrup 60ML price in Pakistan are clearly displayed. Multiple Karachi branches with same-day delivery and nationwide shipping across Pakistan. WhatsApp ordering at each branch. Dawa Healthcare provides genuine allergy medications backed by pharmacist expertise.