HIZONE 1G INJECTION ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Ceftriaxone Sodium 1g

MANUFACTURER: HIGH-Q Pharma

QUANTITY:

Single vial for injection

INDICATION

Hizone 1G Inj is a third-generation cephalosporin antibiotic used to treat serious bacterial infections including community-acquired pneumonia, meningitis, pelvic inflammatory disease, septicemia, surgical prophylaxis, intra-abdominal infections, skin and soft tissue infections, and urinary tract infections caused by susceptible organisms.

MECHANISM OF ACTION

Ceftriaxone is a bactericidal antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), which are enzymes responsible for cross-linking peptidoglycan chains in the bacterial cell wall. This binding blocks transpeptidation, causing defects in the cell wall and ultimately bacterial lysis. Ceftriaxone has excellent stability against many beta-lactamases, a long half-life allowing once-daily dosing, and good penetration into the cerebrospinal fluid, making it effective for CNS infections.

DOSAGE AND ADMINISTRATION

•      Adults: 1 to 2g once daily by intravenous or intramuscular injection

•      Meningitis: 2g every 12 hours initially

•      Gonorrhea: 250mg to 500mg single intramuscular dose

•      Always administered by a healthcare professional; dosage adjusted based on infection severity and renal function

SIDE EFFECTS

Common:

•      Pain and tenderness at injection site

•      Diarrhoea

•      Nausea

•      Elevated liver enzymes (transaminases)

Less common:

•      Clostridium difficile-associated diarrhoea with prolonged use

•      Biliary sludge or pseudolithiasis (particularly in children)

•      Thrombophlebitis with intravenous use

•      Hypersensitivity reactions including rash, urticaria, or anaphylaxis

NOT RECOMMENDED IN

•      Known hypersensitivity to cephalosporins or penicillin’s (cross-reactivity possible)

•      Premature neonates and neonates with jaundice or hyperbilirubinemia (risk of bilirubin displacement)

•      Do not mix with calcium-containing IV solutions in any patient

•      Not for self-administration; hospital or clinic use only

DRUG INTERACTIONS

Concurrent use with aminoglycoside antibiotics such as gentamicin increases nephrotoxicity risk; monitor renal function closely. Ceftriaxone forms a potentially fatal precipitate with calcium-containing solutions, including Ringer's lactate; never mix. Probenecid may reduce renal excretion of ceftriaxone, increasing its plasma levels. Vitamin K antagonists such as warfarin may have enhanced anticoagulant effects with ceftriaxone.

STORAGE INSTRUCTIONS

Store unconstituted vials below 25°C. Protect from light. Reconstituted solution should be used immediately or within stated stability window. Keep out of reach of children.

WHERE TO BUY

You can buy Hizone 1g Inj online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Hizone 1g Inj price in Pakistan and learn about Hizone 1g Inj uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Hizone 1g Inj uses, pricing, and order placement.