GEN-M 60MG INJECTION ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Artesunate 60mg

MANUFACTURER: Genix Pharma

QUANTITY:

Single vial

INDICATION

Gen-M 60mg Inj is an injectable artesunate formulation used for the treatment of severe and complicated Plasmodium falciparum malaria in patients who cannot take oral therapy. The 60mg dose is commonly used for weight-based dosing in pediatric patients and low body weight adults. Artesunate injection is the WHO-recommended first-line treatment for severe malaria, having demonstrated significantly lower mortality than quinine in large clinical trials.

MECHANISM OF ACTION

Same as Gen-M 120mg Injection. Artesunate is rapidly hydrolyzed to dihydroartemisinin (DHA), which generates reactive oxygen species inside malaria-infected erythrocytes, causing rapid killing of all erythrocytic stages including early ring forms that are sequestered in the microvasculature. This ring-stage activity is a key advantage over quinine and explains artesunate's superior efficacy in reducing mortality from severe malaria. The 60mg dose provides the standard 2.4mg/kg loading dose for patients weighing approximately 25kg.

DOSAGE AND ADMINISTRATION

•      Severe malaria: 2.4mg/kg IV or IM at 0, 12, and 24 hours, then once daily

•      60mg loading dose for patients weighing approximately 25kg

•      Children under 20kg: use 3mg/kg per dose

•      Administer into the anterior thigh (IM) or slowly IV over 1 to 2 minutes

•      Minimum 3 parenteral doses before switching to oral ACT

•      Switch to oral antimalarial therapy as soon as the patient can tolerate oral medications

SIDE EFFECTS

Common:

•      Post-artesunate delayed hemolysis (1 to 4 weeks after treatment)

•      Injection site pain

•      Nausea, vomiting

•      Dizziness, headache

Less common:

•      Transient neutropenia

•      Elevated liver enzymes

•      Reticulocytopenia

•      Hypersensitivity reactions (rare)

NOT RECOMMENDED IN

•      Hypersensitivity to artesunate or artemisinin derivatives

•      Not for prophylaxis: only for treatment of active severe malaria

•      First trimester pregnancy: use only if life-threatening and no safer alternative

DRUG INTERACTIONS

Fewer drug interactions than quinine. Avoid mefloquine within 24 hours. Use caution with other QT-prolonging agents. Rifampicin may reduce DHA levels.

STORAGE INSTRUCTIONS

Store Gen-M 60mg Inj vials below 30°C. Protect from light. Do not freeze. Use reconstituted solution within 1 hour. Keep out of reach of children.

WHERE TO BUY

You can buy Gen-M Inj 60mg online from Dawa Healthcare, your trusted provider of hospital-grade antimalarial medications in Pakistan. Check the Gen-M Inj 60mg price in Pakistan and learn about Gen-M Inj 60mg uses through our qualified pharmacists. Dawa Healthcare Pharmacy offers in-house clinic, lab, and medicines all under one roof. Same-day delivery is available in Karachi. Injections are available for Karachi delivery only. Dawa Healthcare Pharmacy has multiple branches all over the country, each with its own dedicated WhatsApp number for easy ordering and consultation.