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EBALIN 50MG CAPSULE

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EBALIN 50MG CAPSULE

EBALIN 50MG CAPSULE ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Pregabalin 50mg

MANUFACTURER: Core Health

QUANTITY:

Pack of 14 capsules

INDICATION

Ebalin 50mg Cap is indicated for the management of neuropathic pain including diabetic peripheral neuropathy and postherpetic neuralgia, as adjunctive therapy for partial-onset seizures in adults, and for the treatment of fibromyalgia and generalized anxiety disorder. The 50mg dose is used in patients requiring a starting or low maintenance dose, particularly those with renal impairment.

MECHANISM OF ACTION

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in central nervous system neurons. This reduces calcium influx at synaptic terminals, decreasing the excessive release of excitatory neurotransmitters including glutamate, substance P, and norepinephrine. The resulting dampening of neuronal hyperexcitability produces analgesic effects in neuropathic pain states and anticonvulsant effects in epilepsy.

DOSAGE AND ADMINISTRATION

      Neuropathic pain: 50mg three times daily initially; increase to 100mg three times daily after one week

      Fibromyalgia: 50mg three times daily; may increase to 100mg three times daily based on response

      Partial seizures (adjunct): 50mg to 100mg two to three times daily

      Take with or without food

      Dose reduction required based on creatinine clearance in renal impairment

SIDE EFFECTS

Common:

      Dizziness, somnolence

      Weight gain, peripheral oedema

      Blurred vision

      Dry mouth, constipation

Less common:

      Cognitive impairment, memory difficulties

      Euphoria

      Ataxia

      Respiratory depression with CNS depressants

NOT RECOMMENDED IN

      Known hypersensitivity to pregabalin or gabapentin

      Severe renal impairment without dose adjustment

      Use with caution in heart failure with oedema

      Not recommended in pregnancy without specialist advice

DRUG INTERACTIONS

Additive CNS depression with opioids, benzodiazepines, and alcohol. Thiazolidinediones increase the risk of peripheral oedema and weight gain. No significant cytochrome P450 interactions.

STORAGE INSTRUCTIONS

Store Ebalin 50mg capsules at room temperature below 30°C. Protect from moisture. Keep in original blister packaging. Store out of reach of children.

WHERE TO BUY

Buy Ebalin 50mg Capsule online from Dawa Healthcare Pharmacy for neuropathic pain relief in Pakistan. Check the Ebalin 50mg capsule price in Pakistan and learn about Ebalin 50mg capsule uses from our team. Same-day delivery in Karachi. Nationwide delivery through Dawa Healthcare Pharmacy.

 

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From $66.50

Original: $190.00

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EBALIN 50MG CAPSULE

$190.00

$66.50

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Description

EBALIN 50MG CAPSULE ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Pregabalin 50mg

MANUFACTURER: Core Health

QUANTITY:

Pack of 14 capsules

INDICATION

Ebalin 50mg Cap is indicated for the management of neuropathic pain including diabetic peripheral neuropathy and postherpetic neuralgia, as adjunctive therapy for partial-onset seizures in adults, and for the treatment of fibromyalgia and generalized anxiety disorder. The 50mg dose is used in patients requiring a starting or low maintenance dose, particularly those with renal impairment.

MECHANISM OF ACTION

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in central nervous system neurons. This reduces calcium influx at synaptic terminals, decreasing the excessive release of excitatory neurotransmitters including glutamate, substance P, and norepinephrine. The resulting dampening of neuronal hyperexcitability produces analgesic effects in neuropathic pain states and anticonvulsant effects in epilepsy.

DOSAGE AND ADMINISTRATION

      Neuropathic pain: 50mg three times daily initially; increase to 100mg three times daily after one week

      Fibromyalgia: 50mg three times daily; may increase to 100mg three times daily based on response

      Partial seizures (adjunct): 50mg to 100mg two to three times daily

      Take with or without food

      Dose reduction required based on creatinine clearance in renal impairment

SIDE EFFECTS

Common:

      Dizziness, somnolence

      Weight gain, peripheral oedema

      Blurred vision

      Dry mouth, constipation

Less common:

      Cognitive impairment, memory difficulties

      Euphoria

      Ataxia

      Respiratory depression with CNS depressants

NOT RECOMMENDED IN

      Known hypersensitivity to pregabalin or gabapentin

      Severe renal impairment without dose adjustment

      Use with caution in heart failure with oedema

      Not recommended in pregnancy without specialist advice

DRUG INTERACTIONS

Additive CNS depression with opioids, benzodiazepines, and alcohol. Thiazolidinediones increase the risk of peripheral oedema and weight gain. No significant cytochrome P450 interactions.

STORAGE INSTRUCTIONS

Store Ebalin 50mg capsules at room temperature below 30°C. Protect from moisture. Keep in original blister packaging. Store out of reach of children.

WHERE TO BUY

Buy Ebalin 50mg Capsule online from Dawa Healthcare Pharmacy for neuropathic pain relief in Pakistan. Check the Ebalin 50mg capsule price in Pakistan and learn about Ebalin 50mg capsule uses from our team. Same-day delivery in Karachi. Nationwide delivery through Dawa Healthcare Pharmacy.