Dosteril 37.5/325mg Tablets Online At Best Price In Pakistan

GENERIC NAME: Tramadol HCl + Paracetamol (37.5mg + 325mg)

MANUFACTURER: Horizon Pharmaceuticals

QUANTITY:

30 tablets per pack

INDICATION:

 Dosteril 37.5/325mg tablet is indicated for moderate to moderately severe pain, including musculoskeletal pain, post-operative pain, dental pain, and chronic pain conditions. The combination of tramadol and paracetamol provides synergistic analgesic effects: tramadol acts centrally to alter pain perception, while paracetamol reduces peripheral pain and fever. It is suitable for short-term use or controlled long-term use under medical supervision.

MECHANISM OF ACTION:

 Tramadol is a centrally acting opioid analgesic that binds to µ-opioid receptors in the CNS and inhibits reuptake of serotonin and norepinephrine. Paracetamol is a non-opioid analgesic and antipyretic that inhibits prostaglandin synthesis in the CNS, reducing pain and fever. Together, they provide effective pain relief through central and peripheral mechanisms.

DOSAGE AND ADMINISTRATION:

●     Take one tablet every 6–8 hours as needed for pain.

●     Maximum 8 tablets per 24 hours.

●     Swallow whole with water; may be taken with or without food.

●     Do not exceed the recommended dose to prevent liver toxicity.

SIDE EFFECTS:

●     Common: nausea, dizziness, constipation, drowsiness, headache, dry mouth.

●     Less common: seizures, allergic reactions, respiratory depression (overdose), liver enzyme elevation.

NOT RECOMMENDED IN:

●     Severe hepatic or renal impairment.

●     History of opioid allergy, seizure disorders, or MAOI use.

●     Pregnant or breastfeeding women without physician guidance.

DRUG INTERACTIONS:

May interact with MAO inhibitors, SSRIs, other CNS depressants, alcohol, or anticoagulants, increasing the risk of serotonin syndrome, respiratory depression, bleeding, or CNS sedation.

STORAGE INSTRUCTIONS:

●     Store at 20–25°C, dry and away from sunlight.

●     Keep out of reach of children.

WHERE TO BUY:

You can conveniently buy Dosteril 37.5/325 mg tablets online in Pakistan with same-day delivery available in Karachi. Easily check the Dosteril 37.5/325 mg tablets price in Pakistan and place your order directly through Dawa Healthcare Pharmacy for a secure and hassle-free experience. Our branches across the country provide prompt WhatsApp support, so you can get quick answers to your queries and confirm your order effortlessly. With reliable packaging and fast dispatch, your medication will reach your doorstep safely and on time.