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DIAJARD-M 12.5/1000MG 14S

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DIAJARD-M 12.5/1000MG 14S

DIAJARD-M 12.5/1000MG ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Empagliflozin 12.5mg + Metformin HCl 1000mg

MANUFACTURER: Highnoon Laboratories Ltd.

QUANTITY

14 tablets

INDICATION

Diajard-M 12.5/1000mg is a dual oral antidiabetic combination indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are not adequately controlled on metformin alone or already on both empagliflozin and metformin as separate tablets.

MECHANISM OF ACTION

Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that reduces blood glucose by blocking glucose reabsorption in the renal proximal tubule, leading to glucosuria. This mechanism is insulin-independent. Metformin reduces hepatic glucose output via activation of AMP-activated protein kinase (AMPK) and improves peripheral insulin sensitivity. The combination provides complementary glycemic control with the added cardiovascular and renal benefits associated with SGLT2 inhibitor therapy.

DOSAGE AND ADMINISTRATION

·        One tablet orally twice daily with meals or as directed by the physician. Swallow whole without crushing or chewing.

·        The dose is individualized based on current antidiabetic therapy, renal function, and glycemic response.

·        Regular monitoring of renal function and blood glucose is required.

SIDE EFFECTS

Common:

      Nausea, vomiting, or diarrhea, particularly at initiation

      Urinary tract infections

      Genital mycotic infections

Less common:

      Volume depletion or hypotension, particularly in the elderly

      Hypoglycemia when combined with insulin or sulphonylureas

      Increased urinary frequency

NOT RECOMMENDED IN

      Renal impairment with eGFR below 30 ml/min/1.73m2

      Type 1 diabetes or diabetic ketoacidosis

      Hypersensitivity to empagliflozin or metformin

      Radiologic contrast requiring iodine within 48 hours

DRUG INTERACTIONS

      Diuretics may increase risk of dehydration with empagliflozin component

      Cimetidine may increase metformin levels

STORAGE INSTRUCTIONS

Store below 25 degrees Celsius in a dry place. Keep in original packaging. Protect from moisture. Keep out of reach of children.

WHERE TO BUY

You can find Diajard-M 12.5/1000mg 14S at dawahealthcare.biz, where all products are verified for quality and authenticity. Whether you need it for its Diajard-M 12.5/1000mg price in pakistan or want to check the Diajard-M 12.5/1000mg uses, our team is available seven days a week to assist you. We offer same-day delivery within Karachi, and nationwide courier service for customers across Pakistan. You can also visit any of our Karachi branches or reach us instantly via WhatsApp for quick order placement.

 

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From $41.89

Original: $119.70

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DIAJARD-M 12.5/1000MG 14S

$119.70

$41.89

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Description

DIAJARD-M 12.5/1000MG ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Empagliflozin 12.5mg + Metformin HCl 1000mg

MANUFACTURER: Highnoon Laboratories Ltd.

QUANTITY

14 tablets

INDICATION

Diajard-M 12.5/1000mg is a dual oral antidiabetic combination indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are not adequately controlled on metformin alone or already on both empagliflozin and metformin as separate tablets.

MECHANISM OF ACTION

Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that reduces blood glucose by blocking glucose reabsorption in the renal proximal tubule, leading to glucosuria. This mechanism is insulin-independent. Metformin reduces hepatic glucose output via activation of AMP-activated protein kinase (AMPK) and improves peripheral insulin sensitivity. The combination provides complementary glycemic control with the added cardiovascular and renal benefits associated with SGLT2 inhibitor therapy.

DOSAGE AND ADMINISTRATION

·        One tablet orally twice daily with meals or as directed by the physician. Swallow whole without crushing or chewing.

·        The dose is individualized based on current antidiabetic therapy, renal function, and glycemic response.

·        Regular monitoring of renal function and blood glucose is required.

SIDE EFFECTS

Common:

      Nausea, vomiting, or diarrhea, particularly at initiation

      Urinary tract infections

      Genital mycotic infections

Less common:

      Volume depletion or hypotension, particularly in the elderly

      Hypoglycemia when combined with insulin or sulphonylureas

      Increased urinary frequency

NOT RECOMMENDED IN

      Renal impairment with eGFR below 30 ml/min/1.73m2

      Type 1 diabetes or diabetic ketoacidosis

      Hypersensitivity to empagliflozin or metformin

      Radiologic contrast requiring iodine within 48 hours

DRUG INTERACTIONS

      Diuretics may increase risk of dehydration with empagliflozin component

      Cimetidine may increase metformin levels

STORAGE INSTRUCTIONS

Store below 25 degrees Celsius in a dry place. Keep in original packaging. Protect from moisture. Keep out of reach of children.

WHERE TO BUY

You can find Diajard-M 12.5/1000mg 14S at dawahealthcare.biz, where all products are verified for quality and authenticity. Whether you need it for its Diajard-M 12.5/1000mg price in pakistan or want to check the Diajard-M 12.5/1000mg uses, our team is available seven days a week to assist you. We offer same-day delivery within Karachi, and nationwide courier service for customers across Pakistan. You can also visit any of our Karachi branches or reach us instantly via WhatsApp for quick order placement.