BOFERIN 500MG/10ML INJECTION ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Ferric Carboxymaltose 500mg/10ml Intravenous Solution

MANUFACTURER: Bosch Pharmaceuticals (Pvt) Ltd

QUANTITY:

Single vial, 10ml

INDICATION

Boferin 500mg/10ml Inj is a high-dose intravenous iron preparation indicated for the treatment of iron-deficiency anemia in patients where oral iron therapy is insufficient, not tolerated, or not clinically feasible. It is specifically indicated in patients with chronic kidney disease, heart failure, inflammatory bowel disease, post-partum iron deficiency anemia, and in patients with severe iron deficiency requiring rapid iron repletion. Its ability to deliver up to 1000mg of iron in a single dose makes it particularly efficient.

MECHANISM OF ACTION

Ferric carboxymaltose is an iron-carbohydrate complex where polynuclear iron (III)-hydroxide is stabilized by a carboxymaltose shell. After intravenous administration, the complex is taken up by the reticuloendothelial system (primarily liver, spleen, and bone marrow macrophages) via endocytosis. The carboxymaltose shell is gradually metabolized, releasing iron which binds to transferrin and is transported to erythroid precursors for hemoglobin synthesis. The slow, controlled release of iron from the carboxymaltose complex allows large doses to be given safely in a short infusion, minimizing free iron toxicity and anaphylaxis risk.

DOSAGE AND ADMINISTRATION

•      Adults: up to 1000mg iron (2 vials of 500mg) by slow IV infusion over 15 minutes, once weekly until the calculated total iron deficit is replenished

•      Maximum single dose: 1000mg iron

•      Administer by slow intravenous injection or infusion; never administer intramuscularly

•      All doses calculated using the Ganzoni formula based on body weight and baseline hemoglobin; prescribed and administered by healthcare professionals

SIDE EFFECTS

Common:

•      Hypophosphatasemia (low phosphate) with repeated dosing; monitor serum phosphate

•      Nausea, vomiting, and abdominal pain

•      Headache and dizziness

•      Transient hypotension with rapid infusion

Less common:

•      Hypersensitivity reactions including anaphylactoid reactions (rare but serious; have resuscitation equipment available)

•      Skin discoloration and pruritus at the injection site if extravasation occurs

•      Arthralgia and myalgia

•      Iron overload with excessive cumulative dosing

NOT RECOMMENDED IN

•      Iron overload conditions (haemochromatosis)

•      Anemia not caused by iron deficiency

•      Known hypersensitivity to ferric carboxymaltose or any excipient

•      First trimester of pregnancy

DRUG INTERACTIONS

Oral iron supplements should not be started within 5 days of intravenous iron to avoid interaction with transferrin binding sites. ACE inhibitors may increase systemic reactions to intravenous iron preparations. Do not mix with other medications or solutions other than normal saline.

STORAGE INSTRUCTIONS

Store below 25°C. Do not freeze. Protect from light. Use immediately after opening. Keep out of reach of children.

WHERE TO BUY

You can buy Boferin 500mg/10ml online from Dawa Healthcare Pharmacy at dawahealthcare.biz, one of Pakistan's most trusted pharmacies for authentic, pharmacist-verified medicines. Browse our product page to check the current Boferin 500mg/10ml injection price in pakistan, read detailed clinical information, and place your order from the comfort of your home. Our experienced pharmacist is always available to answer your questions about Boferin 500mg/10ml injection uses and correct dosage. Customers in Karachi enjoy same-day delivery on orders placed before the daily cutoff, while customers across Pakistan benefit from our nationwide courier service for safe and timely delivery to any city. You can also visit any of our Karachi branches in person or reach our dedicated WhatsApp support team for instant help with Boferin 500mg/10ml injection uses, pricing, prescriptions, and order placement.